Overview

2002 - RJX TECHNOLOGY

Reven Pharmaceutical's RJX Technology Concept is Born.

2008 - COMPASSIONATE CARE

First Patent filed following milestone of RJX administration to over 1,000 compassionate care patients in South Africa.

2013 - MANUFACTURING

Initiated formal manufacturing process in support of FDA new drug development pathway.

2016 - GLOBAL OUTREACH

Filed Investigational New Drug (IND) application & working with over 20 research organizations globally.

2018 - FURTHER RESEARCH

Research initiated to explore RJX for future applications like Vascular, Oncology, CNS, and Ocular disease.

2019 - PHASE 1 CONCLUSION

Phase 1 study concluded and over 10 patents granted nationally & internationally.

2021 - PHASE 2A/2B COVID STUDY

Started and completed Phase 2A and started Phase 2B double-blind placebo study

Scientific Focus

Engineering pharmacological solutions targeting the root cause of disease rather than focusing on alleviating symptoms

At Reven, we are constantly exploring ways to make a meaningful impact for the patients we serve. We are pushing the boundaries on what science and technology can do in hopes of making the impossible, possible.

Peter Lange

Founder & CEO

Potential Target Therapeutic Areas

Reven views RJX as a tool to serve distinct families of potential modalities, with each focusing on different diseases across therapeutic areas. The goal then is to develop our RJX technology platform to revolutionize medicine as applied towards many diseases. The RJX platform supports design of medicines for a diverse array of applications by scientifically grouping shared product features and recognizing areas where customization may further improve outcomes. Reven believes the design of the RJX platform technology will enable us to develop diverse therapies for an array of medical indications

Research

In 2008, Reven initiated compassionate care use with RJX technology in South Africa for patients with limited to no therapeutic options. This opportunity to aid patients also greatly improved Reven’s understanding of the product, enhancing knowledge in areas of dosing, product stabilization, patient healing trajectories, and outcome analysis.

Reven’s recent drug provision through the Australian Government’s Therapeutic Goods Administration Special Access Scheme and pilot research completed in companion animals has fueled Reven’s knowledge base in support of further investigations into RJXs capacity for multiple treatment modalities.

10+ years of research now including data generated from Reven’s Phase 1 Food and Drug Administration (FDA) approved clinical safety study (ClinicalTrials.gov; ID NCT03680105), continues to provide insight into the capabilities of the RJX technology. Reven is assessing further insights and efficacy through a Phase 1 /2 COVID-19 ARDS/Sepsis study (ClinicalTrials.gov; ID NCT04708340) currently enrolling patients in several clinical trial sites throughout the US.

Pipeline

Reven is dedicated to investigating neglected diseases with unmet therapeutic needs and areas of medicine where current standard of care is often not successful. Our goal is to deliver innovative medicines based on the RJX technology to patients in need.

Social Accountability

Our mission is dedicated to the service of patients and the families who cherish them. Collaboration with academia, clinical researchers, providers and patients to address unmet medical needs continues to educate and humble us.

Reven’s overall goal is to advance patient survivability and improve patient quality of life demonstrated by reduced pain, removal of disease, enhanced mobility, increased vitality, improved quality of rest, and restoration of body balance so that patients can re-engage with their lives.

"We have been inspired by our compassionate care patients and the progress they made. Seeing them take that first step without pain was life changing for them and for us. It is our mission and our passion to change lives for the better."